Indole-3-methanol

Tsanangudzo Pfupi

Indole-3-methanol itsva yechipiri chirimwa metabolite inogadzirwa mucruciferous miriwo, iyo inogona kutorwa kubva kune cruciferous miriwo (yakadai sebroccoli, radish uye cauliflower).Indole-3-carbinol ibundu chemopreventive substance.Indole-3-carbinol inogona kutadzisa kuitika uye kukura kwemhando dzakasiyana dzemamota.Indole-3-methanol yakashandiswa encapsulate poly lactic acid co glycolic acid (PLGA) kudzidza ayo anticancer mhedzisiro pazamu adenocarcinoma epithelial masero (MCF7), colon adenocarcinoma epithelial masero (Caco2) uye prostate cancer epithelial masero (PC3) in vitro.Inoshandiswawo se inducer ye cytochrome P4501A (CYP1A).

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Tsanangudzo

Indole-3-methanol (I3C) inoshandisa inonhuhwirira hydrocarbon receptor (AHR) uye induces G1 cell cycle kusungwa uye apoptosis.Naizvozvo, inogona kuita anticancer agent.Mukuwedzera, inokonzera estradiol metabolism nekukurudzira cytochrome P450 enzyme.Naizvozvo, I3C inoonekwa senge inoshanda chemotherapy mushonga wemhando dzakasiyana dzekenza, kusanganisira kenza yemazamu, kenza yeprostate, kenza yekoloni uye leukemia.Indole-3-methanol inogona chete kukurudzira apoptosis yekenza maseru, ayo akachengeteka uye asiri cytotoxic kune asiri bundu masero.Nekuda kwekuita kwayo kwakanyanya, isiri-chepfu uye yakasikwa anti-tumor zvivakwa, indole-3-methanol inogona kushandiswa semumwe wevanoda kudzivirira kenza uye mishonga yekurapa.

Product Info

Cas Nhamba :700-06-1

Kuchena: ≥98%

Fomula:C9H9NO

Formula Wt.:147.17

Kemikari Zita: INDOLE-3-CARBINOL

Synonym: Indole-3-carbinol, 99.5%; Indole-3-carbinol98%;(1H-Indol-3-yl)-methano;Indol-3-yl-methanol;3-INDOLAMETHChemicalbookANOL;INDOLE-3-CARBINOL: 3-INDOLEMETHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL)

Kunyungudika: 96-99 °C

Kuvira nzvimbo: 267.28°C

Chitarisiko: Kunze-kuchena kune yero-orenji crystalline poda kana flakes